
Research-backed peptide information you can trust.
Safety data, evidence ratings, and plain-English explanations for 89 peptides. Every claim cited. Every risk disclosed. Updated regularly.
FDA-approved synthetic PTHrP(1-34) analog that stimulates new bone formation and reduces vertebral (86% RRR) and nonvertebral (43% RRR) fracture risk in postmenopausal women with osteoporosis (PMID 27533157, NCT01343004).
FDA-approved synthetic 32-amino-acid polypeptide identical to salmon calcitonin, used for postmenopausal osteoporosis, Paget's disease, and hypercalcemia. Intranasal 200 IU reduced new vertebral fractures by 33% versus placebo in the PROOF trial (N=1255; PMID 10996576). Well-documented analgesic properties for vertebral compression fracture pain. Considered second-line due to modest efficacy versus newer agents and a cancer risk signal with long-term use (FDA Label).
FDA-approved synthetic decapeptide GnRH antagonist used to inhibit premature LH surges during controlled ovarian stimulation for IVF, with 0.25 mg daily established as the minimal effective multidose regimen (FDA label ANDA218150; PMID 9130900).
FDA-approved (March 2021) glucagon receptor agonist analog for the treatment of severe hypoglycemia in pediatric (age 6+) and adult patients with diabetes, marketed as Zegalogue (PMID 34047955; NDA 214231).
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