Peptides for Gut Health

Peptides researched for gastrointestinal repair, gut lining integrity, and digestive function.

9 peptides

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Linaclotide (Linzess)

FDA Approved

Linaclotide is an FDA-approved 14-amino acid oral GC-C agonist indicated for IBS-C in adults and pediatric patients 7 years and older, chronic...

Gut Health

Plecanatide (Trulance)

FDA Approved

Plecanatide (Trulance) is an FDA-approved oral 16-amino acid synthetic analog of human uroguanylin that activates guanylate cyclase-C receptors on...

Gut Health

Teduglutide (Gattex / Revestive)

FDA Approved

Teduglutide is an FDA- and EMA-approved GLP-2 receptor agonist indicated for Short Bowel Syndrome (SBS) in adults and pediatric patients aged 1 year...

Gut HealthWeight Loss

Apraglutide

Strong Evidence

Apraglutide is a novel, long-acting synthetic glucagon-like peptide-2 (GLP-2) analog designed for once-weekly subcutaneous dosing, under clinical...

Injury & RecoveryGut Health

Glepaglutide

Strong Evidence

Glepaglutide is a novel long-acting glucagon-like peptide-2 (GLP-2) analogue developed by Zealand Pharma for the treatment of short bowel syndrome...

Gut Health

VIP (Vasoactive Intestinal Peptide); Aviptadil (synthetic VIP); ZYESAMI; RLF-100

Moderate Evidence

VIP is a 28-amino acid endogenous neuropeptide and high-affinity agonist at VPAC1 (EC50 0.02-0.03 nM) and VPAC2 (EC50 0.05-0.087 nM) receptors. Acts...

Immune HealthNeurological HealthInjury & RecoveryGut Health

BPC-157

Limited Human Data

BPC-157 is a synthetic pentadecapeptide derived from human gastric juice protein BPC that demonstrates broad cytoprotective, angiogenic, and...

Injury & RecoveryMuscle & PerformanceGut HealthImmune Health

BPC-157 (Pentadecapeptide)

Limited Human Data

BPC-157 is a synthetic 15-amino-acid peptide derived from human gastric juice protein BPC that demonstrates broad cytoprotective, pro-angiogenic, and...

Injury & RecoveryMuscle & PerformanceGut HealthNeurological Health

KPV

Animal Studies Only

C-terminal tripeptide fragment (residues 11-13) of alpha-melanocyte stimulating hormone (alpha-MSH) with potent anti-inflammatory activity mediated...

Gut HealthImmune HealthInjury & Recovery