Peptides for Gut Health
Peptides researched for gastrointestinal repair, gut lining integrity, and digestive function.
Important
This page lists peptides that have been studied in the context of gut health research. Inclusion does not mean a peptide is safe, effective, approved, or recommended.
Do not use this page to make health decisions. Always consult a licensed healthcare provider.
8 peptides
Linaclotide (Linzess)
FDA ApprovedAn FDA-approved daily capsule (Linzess) that relieves constipation and belly pain in people with irritable bowel syndrome with constipation (IBS-C)...
Plecanatide (Trulance)
FDA ApprovedAn FDA-approved daily tablet (Trulance) for adults with chronic constipation or IBS with constipation. It works by mimicking a natural intestinal...
Teduglutide (Gattex / Revestive)
FDA ApprovedAn FDA-approved injection (Gattex in the US, Revestive in Europe) for adults and children as young as 1 year old with short bowel syndrome who depend...
Apraglutide
Late-Stage ClinicalAn investigational once-weekly injection being developed for short bowel syndrome -- a condition where the intestine cannot absorb enough nutrients...
Glepaglutide
Late-Stage ClinicalAn investigational once-weekly injection being developed to help people with short bowel syndrome absorb more nutrients from food, reducing their...
VIP (Vasoactive Intestinal Peptide); Aviptadil (synthetic VIP); ZYESAMI; RLF-100
Early ClinicalA natural peptide that relaxes blood vessels, reduces inflammation, and protects nerve cells throughout the body and brain. A synthetic version was...
BPC-157
Limited HumanA lab-made peptide derived from a protein found in human stomach fluid that has shown healing effects across multiple body systems -- gut, tendons,...
KPV
PreclinicalA tiny fragment of a natural hormone that has shown strong anti-inflammatory effects in the gut in laboratory and animal studies, by blocking a key...