Peptides for Hormonal Health
Peptides investigated for hormonal balance, growth hormone secretion, fertility, and endocrine function.
22 peptides
Cetrorelix (Cetrotide)
FDA ApprovedFDA-approved synthetic decapeptide GnRH antagonist used to inhibit premature LH surges during controlled ovarian stimulation for IVF, with 0.25 mg...
Degarelix (Firmagon)
FDA ApprovedFDA-approved (NDA022201, 2008) synthetic decapeptide GnRH antagonist for advanced prostate cancer that achieves castrate testosterone levels within...
Ganirelix (Orgalutran)
FDA ApprovedFDA-approved (1999) synthetic decapeptide GnRH antagonist used in IVF protocols to prevent premature LH surges during controlled ovarian stimulation,...
Gonadorelin (Factrel, Lutrepulse)
FDA ApprovedSynthetic decapeptide identical to native hypothalamic GnRH; previously FDA-approved as a diagnostic agent (Factrel, NDA018123) and for pulsatile...
Goserelin (Zoladex)
FDA ApprovedFDA-approved synthetic decapeptide GnRH agonist marketed as Zoladex, used for prostate cancer, breast cancer, endometriosis, and endometrial thinning...
Histrelin (Supprelin LA, Vantas)
FDA ApprovedFDA-approved synthetic nonapeptide GnRH agonist delivered as a 50 mg subcutaneous hydrogel implant (Supprelin LA for central precocious puberty,...
Lanreotide (Somatuline Depot)
FDA ApprovedAn FDA-approved long-acting somatostatin analog (brand: Somatuline Depot) indicated for acromegaly, gastroenteropancreatic neuroendocrine tumors...
Leuprolide (Lupron)
FDA ApprovedFDA-approved synthetic GnRH agonist (brand: Lupron, Lupron Depot, Eligard, Vabrinty) used for advanced prostate cancer, endometriosis, uterine...
Liraglutide (Victoza, Saxenda)
FDA ApprovedLiraglutide is an FDA-approved once-daily GLP-1 receptor agonist used for type 2 diabetes (Victoza) and chronic weight management (Saxenda), with...
Nafarelin (Synarel)
FDA ApprovedNafarelin is an FDA-approved synthetic GnRH agonist peptide (~200x more potent than native GnRH) administered intranasally for treatment of...
Octreotide (Sandostatin, Sandostatin LAR, Mycapssa, Bynfezia Pen)
FDA ApprovedOctreotide is an FDA-approved synthetic somatostatin analogue that suppresses growth hormone, IGF-1, and gastrointestinal hormones, used primarily...
PT-141 (Bremelanotide)
FDA ApprovedAn FDA-approved cyclic melanocortin receptor agonist indicated for hypoactive sexual desire disorder (HSDD) in premenopausal women. Marketed as...
Signifor / Signifor LAR (pasireotide)
FDA ApprovedPasireotide (Signifor) is an FDA-approved injectable cyclohexapeptide somatostatin analog with high affinity for SSTR5, indicated for Cushing's...
Teriparatide (Forteo, Forsteo)
FDA ApprovedTeriparatide is an FDA-approved recombinant PTH(1-34) analog that stimulates new bone formation for the treatment of osteoporosis. The pivotal...
Triptorelin (Trelstar / Triptodur / Decapeptyl / Diphereline)
FDA ApprovedTriptorelin is an FDA-approved synthetic GnRH superagonist decapeptide that produces medical castration through pituitary GnRH receptor...
GHRP-2
Moderate EvidenceSynthetic hexapeptide ghrelin receptor (GHS-R1a) agonist that potently stimulates GH release, approved in Japan as a diagnostic agent for GH...
Kisspeptin
Moderate EvidenceKISS1-derived neuropeptide that activates KISS1R upstream of GnRH neurons, rapidly increasing LH and FSH secretion in multiple small human studies in...
Melanotan II
Moderate EvidenceMelanotan II is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone that activates melanocortin receptors MC1R, MC3R,...
MK-677 (Ibutamoren)
Moderate EvidenceMK-677 (ibutamoren) is an orally active, non-peptide growth hormone secretagogue that mimics ghrelin at the GHS-R1a receptor, producing sustained...
Sermorelin (Geref)
Moderate EvidenceA synthetic 29-amino acid analog of endogenous human GHRH that stimulates pituitary growth hormone release. Previously FDA-approved for pediatric GH...
CJC-1295
Limited Human DataA long-acting synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates sustained growth hormone and IGF-1 secretion through a Drug...
Ipamorelin
Limited Human DataA highly selective synthetic pentapeptide agonist of the ghrelin receptor (GHS-R1a) that stimulates robust, pulsatile growth hormone release from the...