Peptides for Longevity & Cellular Health

Peptides studied for age-related decline, cellular repair, and longevity pathways.

9 peptides

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SS-31 (Elamipretide)

Strong Evidence

SS-31 (elamipretide) is a cell-permeable, mitochondria-targeted tetrapeptide that selectively binds cardiolipin on the inner mitochondrial membrane,...

Longevity

GHK (Glycyl-L-Histidyl-L-Lysine)

Moderate Evidence

GHK is a naturally occurring human tripeptide that declines with age, modulates expression of 4,000+ genes toward younger patterns per computational...

Injury & RecoverySkin & HairLongevityImmune Health

Matrixyl

Moderate Evidence

Palmitoyl pentapeptide-4 is a signal peptide that mimics a collagen I degradation fragment (matrikine) to stimulate fibroblast collagen synthesis; a...

LongevitySkin & Hair

Pinealon

Moderate Evidence

A synthetic neuroprotective tripeptide (Glu-Asp-Arg) with limited human and multiple preclinical evidence for reducing oxidative stress and apoptosis...

Neurological HealthLongevity

Sermorelin (Geref)

Moderate Evidence

A synthetic 29-amino acid analog of endogenous human GHRH that stimulates pituitary growth hormone release. Previously FDA-approved for pediatric GH...

LongevityHormonal HealthSleepWeight Loss

Epithalon

Limited Human Data

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Vladimir Khavinson that activates telomerase in human somatic cells and...

LongevitySleep

GHK-Cu

Animal Studies Only

A naturally occurring copper-binding tripeptide that modulates the expression of thousands of human genes, promoting tissue repair, collagen/elastin...

LongevitySkin & HairInjury & RecoveryImmune Health

Humanin

Animal Studies Only

A 24-amino acid mitochondrial-derived peptide (MDP) first discovered in 2001 from surviving neurons of Alzheimer's disease brain tissue, with...

Neurological HealthLongevityWeight LossInjury & Recovery

Livagen

Animal Studies Only

A synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Ala) studied mainly in ex vivo elderly lymphocyte cultures and animal liver models, where it...

Longevity