Peptides for Cardiovascular Health
Peptides studied for heart health, cardiovascular risk reduction, and vascular function.
15 peptides
Dulaglutide (Trulicity)
FDA ApprovedDulaglutide is a once-weekly subcutaneous GLP-1 receptor agonist marketed as Trulicity, FDA-approved for glycemic control in adults and pediatric...
Liraglutide (Victoza, Saxenda)
FDA ApprovedLiraglutide is an FDA-approved once-daily GLP-1 receptor agonist used for type 2 diabetes (Victoza) and chronic weight management (Saxenda), with...
Octreotide (Sandostatin, Sandostatin LAR, Mycapssa, Bynfezia Pen)
FDA ApprovedOctreotide is an FDA-approved synthetic somatostatin analogue that suppresses growth hormone, IGF-1, and gastrointestinal hormones, used primarily...
Oxytocin (Pitocin)
FDA ApprovedOxytocin is an FDA-approved nonapeptide hormone produced in the hypothalamus and released from the posterior pituitary. Clinically used for labor...
Semaglutide (Ozempic, Wegovy, Rybelsus)
FDA ApprovedA long-acting GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Ozempic, Rybelsus) and chronic weight management (Wegovy). Administered...
Tirzepatide (Mounjaro, Zepbound)
FDA ApprovedA first-in-class dual GIP and GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Mounjaro) and chronic weight management (Zepbound)....
Vasopressin (Vasostrict, Pitressin; also known as AVP, ADH)
FDA ApprovedVasopressin (arginine vasopressin, AVP) is an endogenous cyclic nonapeptide hormone and FDA-approved vasopressor that acts via V1a (Ki ~4.70 nM), V1b...
CagriSema
Strong EvidenceInvestigational once-weekly fixed-dose combination of cagrilintide (amylin analog) and semaglutide (GLP-1 agonist) by Novo Nordisk that achieved...
Ecnoglutide
Strong EvidenceA novel cAMP-biased GLP-1 receptor agonist developed by Sciwind Biosciences, approved by China's NMPA for adult type 2 diabetes (January 2026) and...
Retatrutide (LY3437943)
Strong EvidenceRetatrutide (LY3437943) is an investigational triple agonist for the GIP, GLP-1, and glucagon receptors developed by Eli Lilly. Phase 2 trials showed...
Survodutide (BI 456906)
Strong EvidenceSurvodutide is an investigational dual glucagon receptor (GCGR) and GLP-1 receptor (GLP-1R) agonist peptide developed by Zealand Pharma and licensed...
GHRP-6
Moderate EvidenceGHRP-6 is a synthetic hexapeptide ghrelin mimetic that stimulates pulsatile GH release via the GHS-R1a receptor, with multiple small human endocrine...
Hexarelin
Moderate EvidenceSynthetic hexapeptide GH secretagogue that produces rapid, dose-dependent GH release via GHS-R1a activation. The most potent acute GHRP but also...
VIP (Vasoactive Intestinal Peptide); Aviptadil (synthetic VIP); ZYESAMI; RLF-100
Moderate EvidenceVIP is a 28-amino acid endogenous neuropeptide and high-affinity agonist at VPAC1 (EC50 0.02-0.03 nM) and VPAC2 (EC50 0.05-0.087 nM) receptors. Acts...
BPC-157 (Pentadecapeptide)
Limited Human DataBPC-157 is a synthetic 15-amino-acid peptide derived from human gastric juice protein BPC that demonstrates broad cytoprotective, pro-angiogenic, and...